News
Improved CRISPR base editing therapy cuts high cholesterol | PET
1+ hour, 58+ min ago (76+ words) A CRISPR genome editing therapy provides sustained reductions in 'bad' cholesterol in people with inherited high cholesterol or premature coronary artery disease, an early-stage clinical trial shows. by Dr Olivia Goff by Dr Paige Mumford " HFEA 'concerned' about unregulated sperm…...
Two gene therapies for deafness make progress | PET
3+ week, 6+ day ago (322+ words) Dr Mireia Carcol" Estrada A long-term clinical trial of a gene therapy for a rare genetic form of deafness has demonstrated sustained hearing restoration, while a separate gene therapy for the same condition has received approval from the Food and…...
Shetland woman diagnosed with breast cancer following genetic screening | PET
3+ week, 6+ day ago (219+ words) A woman from Shetland has said that genetic testing through a population study helped detect her cancer at an early stage. Christine Glaser, from Lerwick, discovered she carried a harmful variant of the BRCA2 gene after taking part in the Viking…...
Brain organoids could guide treatment of Alzheimer's disease | PET
1+ mon, 4+ day ago (275+ words) Brain organoids, and the tiny particles they secrete, may help to stage early Alzheimer's disease and evaluate drug response. The organoids were also used to assess responses to selective serotonin reuptake inhibitors (SSRIs) " a common class of medication used to…...
Epigenetic changes from colitis may increase colorectal cancer risk | PET
2+ mon, 2+ day ago (248+ words) Epigenetic changes in colon cells caused by colitis can increase susceptibility to developing colorectal cancer in the future. Professor Jason Buenrostro, senior author of this study and a professor of stem cell and regenerative biology at Harvard University, said: 'This…...
World's first approval of i PS cell therapies for commercial use | PET
2+ mon, 1+ week ago (151+ words) Japan's health authorities have granted conditional approval to two therapies developed from induced pluripotent stem cells (i PSCs), to treat Parkinson's disease and heart failure. However, some experts have cautioned that the approval has been granted on the basis of…...
Fertility treatment does not raise overall cancer risk in women | PET
2+ mon, 2+ week ago (395+ words) Women who have undergone fertility treatments show a similar incidence of cancer compared to women of the same age, according to a large Australian study. 'It is very normal for a specific group of people to have a slightly different…...
Gene-targeted drug reduces seizures in children with rare form of epilepsy | PET
2+ mon, 3+ week ago (586+ words) Dravet syndrome is a severe form of epilepsy in children that causes frequent, drug-resistant seizures as well as long-term developmental and cognitive problems. Current medications have been unable to effectively control this condition in most patients. However, a new experimental…...
Genetic map of cat cancers reveals parallels with human disease | PET
2+ mon, 4+ week ago (119+ words) Scientists from the the Wellcome Sanger Institute, Cambridge, have created the first detailed genetic map of cancer in domestic cats, analysing tumour DNA from almost 500 pet cats and examining around 1000 genes linked to 13 types of feline cancer. The study, published…...
NHS announces world-first genetic register for inherited cancer risk | PET
3+ mon, 3+ week ago (310+ words) A new centralised database of genes linked to inherited cancer risk is in development, NHS England announces. 'We are entering a new era of early cancer detection with pioneering research and testing helping us to discover more about how genes…...