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Scientists uncover promising therapeutic target for autoimmune disease affecting the brain
3+ hour, 6+ min ago (460+ words) Scientists have identified a promising target for treatment of a devasting autoimmune disease affecting the brain. The discovery could lead to the development of new therapies for a disease triggered by an attack on one of the key neurotransmitter receptors…...
Study reveals genetic signatures linked to HIV-related cognitive impairment
3+ hour, 13+ min ago (334+ words) Using participant skin cells reprogrammed into neurons, Weill Cornell Medicine researchers have identified genetic signatures associated with HIV infection that may contribute to the cognitive impairment that often occurs in people living with HIV, even when the virus is controlled....
Rare immune events link Epstein Barr virus to early multiple sclerosis damage
3+ hour, 18+ min ago (427+ words) There is mounting evidence that the Epstein-Barr virus may play a part in causing autoimmune diseases like multiple sclerosis. But one puzzle remains: almost everyone gets this virus early in life, yet only a few people ever go on to…...
Engineered vessels boost retinal organoid function, enabling advanced disease modeling
10+ hour, 41+ min ago (353+ words) Until now, it has been difficult to maintain retinal ganglion cells deep inside organoids over extended periods. The supply of nutrients and oxygen in the densely packed tissues is limited, leading to cell death. Engineered vessels boost retinal organoid function,…...
Heart failure care gaps found among Asian American ethnic groups
11+ hour, 28+ min ago (352+ words) Heart failure care gaps found among Asian American ethnic groups'News-Medical Heart failure care gaps found among Asian American ethnic groups Using nearly a decade of data (20152023) from 800+ U.S. hospitals and more than 700,000 patients overall, Northwestern researchers found that when Asian American…...
HIF1 protein identified as key driver of tendon pain
11+ hour, 37+ min ago (408+ words) Overuse of our tendons can cause painful medical conditions for which only limited treatment options exist. Researchers have now deciphered an important molecular mechanism that triggers these problems. Their findings will facilitate the development of new treatments. Complaints such as…...
Post-meal blood sugar spikes linked to increased Alzheimer's risk
12+ hour ago (184+ words) A new study led by researchers from the University of Liverpool has found that spikes in blood sugar after meals may increase the risk of Alzheimer's disease. Whilst research has long suggested that hyperglycaemia, diagnosed type 2 diabetes mellitus and insulin…...
Silent thief of sight: Rutgers Health experts highlight glaucoma risks, early detection
14+ hour, 48+ min ago (573+ words) January is Glaucoma Awareness Month, prompting Rutgers Health experts to underscore the importance of early detection and public awareness. Often progressing silently without noticeable symptoms, it has earned the reputation as the "silent thief of sight." While its progression may…...
Advancing PROTAC development through innovative preclinical model systems
14+ hour, 54+ min ago (835+ words) This article and associated images are based on a poster originally authored by Kieran Casey, Yuzhou Xu, Jichuan Zhang, Shuyue Wang, Yanfei Hu, Ye Tian, Min Lyu, Ziyu Chen, Ya Xu, Qikuan Chen and Yinfei Yin and presented at ELRIG…...
Research shows racial-ethnic differences in the risk of pregnancy-related high blood pressure
16+ hour, 22+ min ago (171+ words) The risk of pregnancy-related high blood pressure varied markedly among subgroups of Asian American, Native Hawaiian and Pacific Islander people, highlighting the need for tailored prevention and treatment, according to research published today in the'Journal of the American Heart Association,…...
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